
Regional bank Fifth Third announced on Tuesday that fintech firm Brex will become the exclusive provider of its commercial cards and expense‑management tools for business clients.
The new program runs on Brex’s embedded‑payments platform, which enables banks to issue corporate cards and automate expense reporting through artificial‑intelligence‑driven workflows, according to a company statement.
This partnership underscores a growing strategic shift in the banking sector: rather than building proprietary AI‑enabled platforms from scratch, many legacy banks are opting to collaborate with fintech specialists that can deliver cutting‑edge functionality at speed. For Fifth Third, the move dovetails with its ongoing acquisition of Comerica—a transaction that will lift the combined entity into the top ten U.S. banks with roughly $288 billion in assets. The scale of the merger provides the capital base needed to invest in technology while also expanding the commercial‑card universe that Brex will serve.
Industry analysts see the collaboration as a win‑win. Brex gains access to a nationwide branch network and a large, credit‑worthy corporate customer base, accelerating its ambitions to capture a larger slice of the $5.6 billion commercial‑card volume market. Fifth Third, meanwhile, can instantly augment its digital product suite, offering AI‑powered spend controls, real‑time invoice reconciliation, and predictive cash‑flow insights—features that are increasingly expected by tech‑savvy midsize enterprises.
“Our partnership with Brex is a commitment to redefine how companies leverage financial technology,” Fifth Third CEO Tim Spence said in a statement. “By combining the strength of a leading bank with Brex’s AI‑driven innovation, we’re creating intelligent solutions that simplify complexity, drive efficiency and enable businesses to scale globally with confidence.”
From a risk‑management perspective, the partnership also helps both firms meet tightening regulatory expectations around transaction monitoring and fraud detection. Brex’s AI engine continuously scans spending patterns to flag anomalous activity, reducing manual oversight and aligning with the Federal Reserve’s emphasis on advanced analytics for financial institutions.
Financial terms of the deal were not disclosed.
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