DeepSomatic

Google introduced DeepSomatic, an open-source AI tool using convolutional neural networks to improve the accuracy of cancer-related mutation identification in tumor genomes. Trained with the high-quality CASTLE dataset, DeepSomatic analyzes genetic variants, distinguishing clinically relevant mutations from noise. It outperforms existing methods, particularly in identifying insertions and deletions (Indels), even in challenging samples. It can also operate in “tumor-only” mode and generalizes well to new cancer types, with the goal of enabling more precise and personalized cancer treatments.